Gra dla fanów mordobić, zombie i oczywiście filmu o tym samym tytule. Pod względem technologicznym nie oferuje zaskakującej jakości grafiki, ale w zamian nie ma kolosalnych wymagań sprzętowych. Ponadto możemy w Resident Evil 5 włączyć generowanie obrazu w trybie DX10.
Resident Evil 5: 1680x1050, Max Detail
Aniso-x16, AA x4
| Sapphire 5870 Toxic 2GB (925/1225) |  136 |
| HIS 5870 TurboX 1GB (900/1225) |  134 |
| MSI 5870 Lighting 1GB (900/1200) | 133 |
| ASUS 5870 Matrix 1GB (894/1200) | 132 |
| Sapphire 5870 Vapor-X 1GB (870/1250) | 129 |
| HIS 5870 Turbo 1GB (875/1225) | 129 |
| Gigabyte 5870 UD 1GB (850/1200) | 126 |
| ASUS 5870 V2 1GB (850/1200) | 126 |
| HIS 5870 iCooler V 1GB (850/1200) | 126 |
| MSI 5850 TwinFrozr II 1GB (725/1000) | 111 |
| Sapphire 5850 Toxic 1GB (765/1125) | 111 |
| HIS 5850 Turbo 1GB (765/1125) | 111 |
| ASUS 5850 TOP 1GB (765/1125) | 111 |
| Zotac GTX 470 1.28GB (608/837) |  104 |
| ASUS GTX 470 1.28GB (608/837) | 104 |
| Gigabyte GTX 285 2GB (660/1200) | 99 |
| MSI 4890 Cyclone 1GB (1000/1000) | 97 |
| Gigabyte 5850 OC 1GB (765/1000) | 96 |
| Gigabyte GTX 260 SO 896MB (680/1250) | 93 |
| MSI GTX 260 Lighting 1.8GB (655/999) | 81 |
| Sapphire 5830 1GB (800/1000) | 81 |
| ASUS 5830 Cu 1GB (800/1000) | 81 |
| Gigabyte 5830 1GB (800/1000) | 81 |
| HIS 5830 iCooler 1GB (800/1000) | 81 |
Resident Evil 5: 1920x1200, Max Detail
Aniso-x16, AA x0
| Sapphire 5870 Toxic 2GB (925/1225) | 120 |
| MSI 5870 Lighting 1GB (900/1200) | 119 |
| HIS 5870 TurboX 1GB (900/1225) | 119 |
| ASUS 5870 Matrix 1GB (894/1200) | 118 |
| Sapphire 5870 Vapor-X 1GB (870/1250) | 117 |
| HIS 5870 Turbo 1GB (875/1225) | 117 |
| Gigabyte 5870 UD 1GB (850/1200) | 115 |
| ASUS 5870 V2 1GB (850/1200) | 115 |
| HIS 5870 iCooler V 1GB (850/1200) | 115 |
| Gigabyte 5850 OC 1GB (765/1000) | 100 |
| ASUS 5850 TOP 1GB (765/1125) | 100 |
| Sapphire 5850 Toxic 1GB (765/1125) | 100 |
| HIS 5850 Turbo 1GB (765/1125) | 100 |
| MSI 5850 TwinFrozr II 1GB (725/1000) | 98 |
| Gigabyte GTX 285 2GB (660/1200) | 97 |
| Zotac GTX 470 1.28GB (608/837) | 94 |
| ASUS GTX 470 1.28GB (608/837) | 94 |
| Gigabyte GTX 260 SO 896MB (680/1250) | 90 |
| MSI 4890 Cyclone 1GB (1000/1000) | 87 |
| MSI GTX 260 Lighting 1.8GB (655/999) | 81 |
| Sapphire 5830 1GB (800/1000) | 75 |
| ASUS 5830 Cu 1GB (800/1000) | 75 |
| Gigabyte 5830 1GB (800/1000) | 75 |
| HIS 5830 iCooler 1GB (800/1000) | 75 |
Resident Evil 5: 1920x1200, Max Detail
Aniso-x16, AA x4
| Sapphire 5870 Toxic 2GB (925/1225) | 113 |
| HIS 5870 TurboX 1GB (900/1225) | 111 |
| MSI 5870 Lighting 1GB (900/1200) | 110 |
| ASUS 5870 Matrix 1GB (894/1200) | 109 |
| Sapphire 5870 Vapor-X 1GB (870/1250) | 108 |
| HIS 5870 Turbo 1GB (875/1225) | 108 |
| Gigabyte 5870 UD 1GB (850/1200) | 106 |
| ASUS 5870 V2 1GB (850/1200) | 106 |
| HIS 5870 iCooler V 1GB (850/1200) | 106 |
| Gigabyte 5850 OC 1GB (765/1000) | 94 |
| ASUS 5850 TOP 1GB (765/1125) | 94 |
| Sapphire 5850 Toxic 1GB (765/1125) | 94 |
| HIS 5850 Turbo 1GB (765/1125) | 94 |
| MSI 5850 TwinFrozr II 1GB (725/1000) | 92 |
| Zotac GTX 470 1.28GB (608/837) | 83 |
| ASUS GTX 470 1.28GB (608/837) | 83 |
| MSI 4890 Cyclone 1GB (1000/1000) | 80 |
| Gigabyte GTX 285 2GB (660/1200) | 80 |
| Gigabyte GTX 260 SO 896MB (680/1250) | 75 |
| Sapphire 5830 1GB (800/1000) | 67 |
| ASUS 5830 Cu 1GB (800/1000) | 67 |
| Gigabyte 5830 1GB (800/1000) | 67 |
| HIS 5830 iCooler 1GB (800/1000) | 67 |
| MSI GTX 260 Lighting 1.8GB (655/999) | 66 |
Resident Evil 5 to gra, w której najsłabiej zaprezentowały się karty graficzne Radeon 5830. Pomimo niezłej architektury wewnętrznej i wysokiego taktowania są w stanie powalczyć co najwyżej ze starym i raczej lekko podkręconym GeForce GTX 260. Starszy układ graficzny – Radeon HD 4890 na „sterydach” mocno przegonił HD 5830 i zrównał się z GeForce GTX 285.
Karty GeForce GTX 470 także nie błyszczą – osiągają wyniki na poziomie niższym niż Radeon 5850. Układy HD 5850 i HD 5870 to czołówka, jeśli chodzi o grę Resident Evil 5.
